Safety and Efficacy of Bilateral Submental Cryolipolysis With Quantified 3-Dimensional Imaging of Fat Reduction and Skin Tightening
Cryolipolysis uses controlled cooling to non invasively damage adipocytes. The selective fat damage results from the greater susceptibility of lipid-rich adipocytes to cold injury compared with surrounding water-rich cells.1-3 Cryolipolysis has been shown to safely and effectively reduce subcutaneous fat and currently hasUS Food and Drug Administration clearance for treatment of the flanks,abdomen,thighs, sub mental area, back, bra area, underneath the buttocks, and arms. Clinical studies have investigated the safety and efficacy of cryolipolysis treatments for subcutaneous fat reduction in numerous areas of the body, including the abdomen, flanks, inner thighs, outer thighs, arms, and chest.4-15 Noninvasive reduction of sub mental fat has currently been an area of interest in aesthetic medicine owing to recent advances in technologies, increased public awareness, and a strong record of safety and efficacy.A previous study of cryolipolysis of the sub mental area demonstrated that the procedure was safe and well tolerated, produced visible improvement to the neck contour, and generated high patient satisfaction.16
Eric F. Bernstein, MD, MSE; Jason D. Bloom, MD
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